Quaternized Polymer-Single-Walled Carbon Nanotube Scaffolds for a Chemiresistive Glucose Sensor

Soylemez S., Yoon B., Toppare L., Swager T. M.

ACS SENSORS, cilt.2, sa.8, ss.1123-1127, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 2 Sayı: 8
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1021/acssensors.7b00323
  • Dergi Adı: ACS SENSORS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1123-1127
  • Anahtar Kelimeler: chemiresistive glucose sensor, single-walled carbon nanotube, poly(4-vinylpyridine), quaternization, glucose oxidase, glucose detection in beverages, BIOSENSORS, COMPOSITES, SYSTEMS
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

A chemiresistive glucose sensor based on poly(4-vinylpyridine) (P4VP) and single-walled carbon nano tube (SWCNT) composites was reported. To fabricate this glucose sensor, a glass substrate containing gold electrodes was treated with 3-bromopropyltrichlorosilane to obtain a covalent bonding between the polymer SWCNT composite and the glass substrate. Some of the pyridyl moieties in P4VP react with the surface, and the remainders were quaternized using 2-bromoethanol to achieve highly charged hydrophilic surface with improved biocompatibility with enzyme molecules. The resulting biomimetic surface was functionalized with glucose oxidase (GOx) by electrostatic assembly with the quaternized P4VP-SWCNT composite. This material displays a decrease in electrical resistance as a result of enzymatically liberated hydrogen peroxide produced in response to glucose, which increases the p-doping of the SWCNT. The sensor exhibited high selectivity for glucose and showed an instant response (within 3 s) to glucose.