Enantioselective synthesis of hydroxy ketones through cleavage and formation of acyloin linkage. Enzymatic kinetic resolution via C-C bond cleavage


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Demir A. , Pohl M., Janzen E., Muller M.

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, sa.7, ss.633-635, 2001 (SCI İndekslerine Giren Dergi) identifier identifier

  • Basım Tarihi: 2001
  • Doi Numarası: 10.1039/b100341k
  • Dergi Adı: JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
  • Sayfa Sayıları: ss.633-635

Özet

Both enantiomers of benzoins and (R)-2-hydroxy-1-phenylpropanone analogues were obtained in high yield on a preparative scale starting from aromatic aldehydes, rac-benzoins and aliphatic aldehydes via enzyme-catalysed C-C bond cleavage and C-C bond formation reactions.