Enantioselective synthesis of hydroxy ketones through cleavage and formation of acyloin linkage. Enzymatic kinetic resolution via C-C bond cleavage

Demir, AYHAN; Pohl, M; Janzen, E; Muller, M

doi:10.1039/b100341k

Enantioselective synthesis of hydroxy ketones through cleavage and formation of acyloin linkage. Enzymatic kinetic resolution via C-C bond cleavage

Atıf İçin Kopyala

Demir A., Pohl M., Janzen E., Muller M.

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, sa.7, ss.633-635, 2001 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Basım Tarihi: 2001
Doi Numarası: 10.1039/b100341k
Dergi Adı: JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.633-635
Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

Both enantiomers of benzoins and (R)-2-hydroxy-1-phenylpropanone analogues were obtained in high yield on a preparative scale starting from aromatic aldehydes, rac-benzoins and aliphatic aldehydes via enzyme-catalysed C-C bond cleavage and C-C bond formation reactions.