Lewis acid catalyzed 1,3-dipolar cycloadditon reactions of stabilized azomethine ylides

DOĞAN Ö., KOYUNCU H., KANIŞKAN Ü.

TURKISH JOURNAL OF CHEMISTRY, vol.25, no.3, pp.365-371, 2001 (SCI-Expanded, Scopus, TRDizin) identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 3
  • Publication Date: 2001
  • Journal Name: TURKISH JOURNAL OF CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.365-371
  • Middle East Technical University Affiliated: Yes

Abstract

Diethylzinc was tested for the first time as the Lewis acid in 1,3-dipolar cycloaddition reactions of azomethine ylides to synthesize pyrrolidine derivatives. A new, easily applicable and highly selective method was developed for the synthesis of highly substituted pyrrolidines. By the application of this method, the synthesis of three new pyrrolidine derivatives was achieved.