Lewis acid catalyzed 1,3-dipolar cycloadditon reactions of stabilized azomethine ylides

DOĞAN Ö., KOYUNCU H., KANIŞKAN Ü.

TURKISH JOURNAL OF CHEMISTRY, cilt.25, sa.3, ss.365-371, 2001 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 3
  • Basım Tarihi: 2001
  • Dergi Adı: TURKISH JOURNAL OF CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.365-371
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

Diethylzinc was tested for the first time as the Lewis acid in 1,3-dipolar cycloaddition reactions of azomethine ylides to synthesize pyrrolidine derivatives. A new, easily applicable and highly selective method was developed for the synthesis of highly substituted pyrrolidines. By the application of this method, the synthesis of three new pyrrolidine derivatives was achieved.