Atıf İçin Kopyala
Demir A., Sesenoglu O., Eren E., Hosrik B., Pohl M., Janzen E., ...Daha Fazla
ADVANCED SYNTHESIS & CATALYSIS, cilt.344, sa.1, ss.96-103, 2002 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
344
Sayı:
1
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Basım Tarihi:
2002
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Doi Numarası:
10.1002/1615-4169(200201)344:1<96::aid-adsc96>3.0.co;2-z
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Dergi Adı:
ADVANCED SYNTHESIS & CATALYSIS
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.96-103
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Anahtar Kelimeler:
benzoin condensation, biocatalyst, carboligation, hydroxy ketones, thiamin diphosphate, FRUCTOSE-DERIVED DIOXIRANE, FLUORESCENS BIOVAR-I, SILYL ENOL ETHERS, BENZOIN CONDENSATION, KINETIC RESOLUTION, THIAZOLIUM SALT, BAKERS-YEAST, BENZOYLFORMATE DECARBOXYLASE, NUCLEOPHILIC ACYLATION, TRIMETHYLSILYL CYANIDE
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Orta Doğu Teknik Üniversitesi Adresli:
Evet
Özet
(R)-Benzoins and (R) -2-hydroxypropiophenone derivatives are formed on a preparative scale by benzaldehyde lyase (BAL)-catalyzed C-C bond formation from aromatic aldehydes and acetaldehyde in aqueous buffer/DMSO solution with remarkable case in high chemical yield and high optical purity. The substrate range of this thiamin diphosphate-dependent enzyme was examined with respect to a broad applicability of this benzoin condensation-type reaction in stereoselective synthesis.