SYNTHESIS AND ANTIFUNGAL ACTIVITY OF SOME NEW BENZIMIDAZOLE DERIVATIVES
ARCHIV DER PHARMAZIE, vol.324, no.5, pp.283-286, 1991 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 324 Issue: 5
- Publication Date: 1991
- Doi Number: 10.1002/ardp.19913240505
- Journal Name: ARCHIV DER PHARMAZIE
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.283-286
- Middle East Technical University Affiliated: No
Abstract
Synthesis and antifungal evaluation of 5-ethoxycarbonyl-2-(substituted-benzyl or phenoxymethyl)benzimidazoles are reported. Structures of the compounds were elucidated with IR-, H-1-NMR-, C-13-NMR-, mass-spectra and elemental analysis. Preliminary results show that none of the synthesized benzimidazole derivatives has antifungal activity at the concentration of 100-mu-g/ml against Candida parapsilosis, Candida stellatoidea, and Candida pseudotropicalis.