TETRAHEDRON-ASYMMETRY, vol.12, no.13, pp.1953-1956, 2001 (SCI-Expanded)
Article / Article
Science Citation Index Expanded (SCI-EXPANDED), Scopus
Middle East Technical University Affiliated:
A chemoenzymatic synthesis of pharmacological interesting (R)-2-hydroxypropiophenones starting from propiophenone derivatives is described. Manganese(III) acetate-mediated acetoxylation followed by fungus-mediated hydrolysis of propiophenone derivatives affords (R)-2-hydroxypropiophenones in high enantiomeric excess. (C) 2001 Elsevier Science Ltd. All rights reserved.