Characterization of Gemcitabine Loaded Polyhydroxybutyrate Coated Magnetic Nanoparticles for Targeted Drug Delivery

Parsian M., MUTLU P., Yalcin S., GÜNDÜZ U.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, vol.20, no.10, pp.1233-1240, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 10
  • Publication Date: 2020
  • Doi Number: 10.2174/1871520620666200310091026
  • Journal Name: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE
  • Page Numbers: pp.1233-1240
  • Keywords: Polyhydroxybutyrate, magnetic nanoparticles, gemcitabine, breast cancer, SKBR-3, MCF-7, targeting drug delivery, POLYHYDROXYALKANOATES, PHARMACOKINETICS, DOXORUBICIN
  • Middle East Technical University Affiliated: Yes

Abstract

Background: Targeted drug delivery is one of the recent hot topics in cancer therapy. Because of having a targeting potential under the magnetic field and a suitable surface for the attachment of different therapeutic moieties, magnetic nanoparticles are widely studied for their applications in medicine.