Metabolic changes in schizophrenia and human brain evolution

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Khaitovich P., Lockstone H. E. , Wayland M. T. , Tsang T. M. , Jayatilaka S. D. , Guo A. J. , ...Daha Fazla

GENOME BIOLOGY, cilt.9, sa.8, 2008 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9 Konu: 8
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1186/gb-2008-9-8-r124


Background: Despite decades of research, the molecular changes responsible for the evolution of human cognitive abilities remain unknown. Comparative evolutionary studies provide detailed information about DNA sequence and mRNA expression differences between humans and other primates but, in the absence of other information, it has proved very difficult to identify molecular pathways relevant to human cognition.