Metabolic changes in schizophrenia and human brain evolution

Khaitovich, Philipp; Lockstone, Helen; Wayland, Matthew; Tsang, Tsz; Jayatilaka, Samantha; Guo, Arfu; Zhou, Jie; Somel, MEHMET; Harris, Laura; Holmes, Elaine; Paeaebo, Svante; Bahn, Sabine

doi:10.1186/gb-2008-9-8-r124

Metabolic changes in schizophrenia and human brain evolution

Khaitovich P., Lockstone H. E., Wayland M. T., Tsang T. M., Jayatilaka S. D., Guo A. J., ...Daha Fazla

GENOME BIOLOGY, cilt.9, sa.8, 2008 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 9 Sayı: 8
Basım Tarihi: 2008
Doi Numarası: 10.1186/gb-2008-9-8-r124
Dergi Adı: GENOME BIOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Orta Doğu Teknik Üniversitesi Adresli: Hayır

Özet

Background: Despite decades of research, the molecular changes responsible for the evolution of human cognitive abilities remain unknown. Comparative evolutionary studies provide detailed information about DNA sequence and mRNA expression differences between humans and other primates but, in the absence of other information, it has proved very difficult to identify molecular pathways relevant to human cognition.