Changes in expression profiles of antioxidant enzymes in diabetic rat kidneys


SADİ G., Eryilmaz N., Tutuncuoglu E., Cingir S., Guray T.

DIABETES-METABOLISM RESEARCH AND REVIEWS, vol.28, no.3, pp.228-235, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 3
  • Publication Date: 2012
  • Doi Number: 10.1002/dmrr.1302
  • Title of Journal : DIABETES-METABOLISM RESEARCH AND REVIEWS
  • Page Numbers: pp.228-235
  • Keywords: diabetes, kidney tissues, antioxidant enzymes, lipoic acid, vitamin C, OXIDATIVE STRESS, MESSENGER-RNA, LIPOIC ACID, VITAMIN-C, CATALASE, INSULIN, TISSUE, ABL, ARG

Abstract

Background In diabetes mellitus, increased formation of reactive oxygen species due to high level of glucose in both blood plasma and tissues creates oxidative stress and damages the tissues. Antioxidants together with the antioxidant enzymes are very important in order to protect the cells against oxidative damage.