Changes in expression profiles of antioxidant enzymes in diabetic rat kidneys


SADİ G., Eryilmaz N., Tutuncuoglu E., Cingir S., Guray T.

DIABETES-METABOLISM RESEARCH AND REVIEWS, cilt.28, sa.3, ss.228-235, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 3
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1002/dmrr.1302
  • Dergi Adı: DIABETES-METABOLISM RESEARCH AND REVIEWS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.228-235
  • Anahtar Kelimeler: diabetes, kidney tissues, antioxidant enzymes, lipoic acid, vitamin C, OXIDATIVE STRESS, MESSENGER-RNA, LIPOIC ACID, VITAMIN-C, INSULIN, TISSUE, CATALASE, ABL, ARG
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

Background In diabetes mellitus, increased formation of reactive oxygen species due to high level of glucose in both blood plasma and tissues creates oxidative stress and damages the tissues. Antioxidants together with the antioxidant enzymes are very important in order to protect the cells against oxidative damage.