Fungi mediated conversion of benzil to benzoin and hydrobenzoin

Demir A., Hamamci H., Ayhan P., Duygu A., Igdir A., Capanoglu D.

TETRAHEDRON-ASYMMETRY, cilt.15, sa.16, ss.2579-2582, 2004 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 16
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1016/j.tetasy.2004.07.010
  • Dergi Adı: TETRAHEDRON-ASYMMETRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2579-2582
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

An enzyme system of four fungi catalyses the reduction of benzil to benzoin, as well as benzoin to hydrobenzoin. Depending on the pH of the medium, both enantiomers of benzoin can be obtained in good yield and high ee starting from benzil via a reduction, as well as from rac-benzoin via a novel deracemization reaction. Starting from benzil, (R)-, (S)- and rac-benzoin only (R,R)-hydrobenzoin was obtained in high ee and chemical yield. (C) 2004 Elsevier Ltd. All rights reserved.