Ring expansion in the coupling of Fischer-carbene complexes with 1-alkynyl-1-hydroxy cyclic compounds

Zora M., Herndon J., Li Y., Rossi J.

TETRAHEDRON, vol.57, no.24, pp.5097-5107, 2001 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 57 Issue: 24
  • Publication Date: 2001
  • Doi Number: 10.1016/s0040-4020(01)00359-3
  • Journal Name: TETRAHEDRON
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.5097-5107
  • Middle East Technical University Affiliated: Yes


The coupling of a variety of transition metal-carbene complexes with alkynols has been studied. In many cases, the intermediate vinylcarbene complexes formed in this reaction undergo a ring expansion to afford cyclic ketone derivatives. This scope and limit of this process is explored. (C) 2001 Elsevier Science Ltd. All rights reserved.