Nanobiomaterial applications in orthopedics

Christenson E. M. , Anseth K. S. , Van Den Beucken L. J. J. P. , Chan C. K. , Ercan B. , Jansen J. A. , ...Daha Fazla

JOURNAL OF ORTHOPAEDIC RESEARCH, cilt.25, ss.11-22, 2007 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1002/jor.20305
  • Sayfa Sayıları: ss.11-22


Advancements in nanobiotechnology are revolutionizing our capability to understand biological intricacies and resolve biological and medical problems by developing subtle biomimetic techniques. Nanocomposites and nanostructured materials are believed to play a pivotal role in orthopedic research since bone itself is a typical example of a nanocomposite. This article reviews current strategies using nanobiomaterials to improve current orthopedic materials and examines their applications in bone tissue engineering. Preliminary investigations support the potential of nanobiomaterials in orthopedic applications; however, significant advancements are necessary to achieve clinical use. Overall, current trends in nanobiotechnology foreshadow a bright future through the use of nanobiomaterials in the orthopedic domain. (c) 2006 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.