A Semantic Transformation Methodology for the Secondary Use of Observational Healthcare Data in Postmarketing Safety Studies


Pacaci A., Gonul S., Sinaci A. A. , Yuksel M., Erturkmen G. B. L.

FRONTIERS IN PHARMACOLOGY, cilt.9, 2018 (SCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 9
  • Basım Tarihi: 2018
  • Doi Numarası: 10.3389/fphar.2018.00435
  • Dergi Adı: FRONTIERS IN PHARMACOLOGY

Özet

Background: Utilization of the available observational healthcare datasets is key to complement and strengthen the postmarketing safety studies. Use of common data models (CDM) is the predominant approach in order to enable large scale systematic analyses on disparate data models and vocabularies. Current CDM transformation practices depend on proprietarily developed Extract-Transform-Load (ETL) procedures, which require knowledge both on the semantics and technical characteristics of the source datasets and target CDM.