Covalently immobilized tris(triazolyl) methanol-Cu(I) complexes: highly active and recyclable catalysts for CuAAC reactions

ÖZKAL E., Oezcubukcu S., JİMENO C., Pericas M. A.

CATALYSIS SCIENCE & TECHNOLOGY, vol.2, no.1, pp.195-200, 2012 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 2 Issue: 1
  • Publication Date: 2012
  • Doi Number: 10.1039/c1cy00297j
  • Journal Name: CATALYSIS SCIENCE & TECHNOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.195-200
  • Middle East Technical University Affiliated: Yes

Abstract

Tris(1-benzyl-1H-1,2,3-triazol-4-yl)methanol (3), a highly efficient ligand for CuAAC reactions, has been immobilized onto Merrifield resins through different strategies. The S(N)2-supported Cu complex (8) is stable in water and under air; it is active at low catalyst loadings (1 mol%) and at low concentration (down to 0.125 M) in both aqueous and purely organic media. Resin 8 can be repeatedly reused in 1 : 1 MeOH-water for short reaction times (4 h) with the only precaution of Cu(I) reloading every five cycles.