Copy For Citation
Dogan O., ZEYTİNCİ S., BULUT A.
SYNTHETIC COMMUNICATIONS, vol.35, no.8, pp.1067-1076, 2005 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
35
Issue:
8
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Publication Date:
2005
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Doi Number:
10.1081/scc-200054207
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Journal Name:
SYNTHETIC COMMUNICATIONS
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Page Numbers:
pp.1067-1076
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Keywords:
alpha-bromoacryloyferrocene, alpha-bromocrotonoylferrocene, aziridines, ferrocenylenones, Gabriel-Cromwell method, 1,3-DIPOLAR CYCLOADDITIONS, ASYMMETRIC-SYNTHESIS, AZOMETHINE YLIDES, CHIRAL AZIRIDINES, ACID-DERIVATIVES, AMINO-ACIDS, ALPHA-AMINO, AZIRIDINE-2-CARBOXYLATES, AUXILIARY, EFFICIENT
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Middle East Technical University Affiliated:
Yes
Abstract
The Gabriel -Cromwell method is applied successfully in the synthesis of ferrocenyl-substituted aziridines. Acryloyl- and crotonoy1ferrocenes are brominated first and then reacted with benzylamine, diisopropylamine, and furfurylamine in the presence of triethylamine. The aziridines are obtained in more than 90% isolated yields.