Gold(I)/Zn(II) catalyzed tandem hydroamination/annulation reaction of 4-yne-nitriles
CHEMICAL COMMUNICATIONS, vol.46, no.42, pp.8032-8034, 2010 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 46 Issue: 42
- Publication Date: 2010
- Doi Number: 10.1039/c0cc02357d
- Journal Name: CHEMICAL COMMUNICATIONS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.8032-8034
- Open Archive Collection: AVESIS Open Access Collection
- Middle East Technical University Affiliated: Yes
Abstract
The tandem hydroamination-annulation reaction of 4-pentyne-nitriles in the presence of amine nucleophiles and a cooperatively operating catalyst system, consisting of Ph(3)PAuCl and Zn(ClO(4))(2), provides an efficient route to 2-aminopyrroles. Two regioisomeric 2-aminopyrroles were formed in moderate to good yields.