Micromeria myrtifolia: The influence of the extracting solvents on phenolic composition and biological activity

Sarikurkcu C., Hanine H., Sarikurkcu R. B., Sarikurkcu R. T., Amarowicz R.

INDUSTRIAL CROPS AND PRODUCTS, vol.145, 2020 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 145
  • Publication Date: 2020
  • Doi Number: 10.1016/j.indcrop.2019.111923
  • Journal Name: INDUSTRIAL CROPS AND PRODUCTS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Biotechnology Research Abstracts, CAB Abstracts, Communication Abstracts, Compendex, Food Science & Technology Abstracts, Geobase, INSPEC, Metadex, Veterinary Science Database
  • Keywords: Micromeria myrtifolia, Enzyme inhibition, Radical scavenging, Phenolic profile, Rosmarinic acid, ANTIMICROBIAL ACTIVITY, IN-VITRO, ANTIOXIDANT ACTIVITIES, ESSENTIAL OILS, MULTIFUNCTIONAL AGENTS, CHEMICAL-COMPOSITION, BIOACTIVE COMPOUNDS, ALPHA-AMYLASE, L., TYROSINASE
  • Middle East Technical University Affiliated: Yes

Abstract

Currently, there is much interest in using the active compounds that exist in plants as natural treatments. The pharmaceutical industry is also looking for novel chemical compounds from natural sources that do not have side effects. The purpose of this study was to identify the antioxidant and enzymatic inhibition activities of different extracts (ethyl acetate, methanol and water) of Micromeria myrtifolia from Turkey. The phenolic constituents in the extracts were also identified using liquid chromatography-electrospray tandem mass spectrometry. The methanol and water extracts were rich in rosmarinic, syringic, chlorogenic, caffeic, and protocatechuic acids, while rosmarinic acid and apigenin were the main compounds in the ethyl acetate extract. Hence, the water extract showed the highest antioxidant activity and total phenol and flavonoid contents, followed by those of the methanol extract. However, inhibition of alpha-amylase and tyrosinase was the most efficient in the methanol extract.