Preparation and application of an s-triazine-based novel N-halamine biocide for antimicrobial fibers

Lee J., Broughton R. M., Akdag A., Worley S. D., Huang T. S.

FIBERS AND POLYMERS, vol.8, no.2, pp.148-154, 2007 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 2
  • Publication Date: 2007
  • Doi Number: 10.1007/bf02875784
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.148-154
  • Keywords: antimicrobial fiber, N-halamine, s-triazine derivative, biocidal fiber, antimicrobial finishing, HOSPITAL FABRICS, SURVIVAL
  • Middle East Technical University Affiliated: Yes


N-halamines serve as important antimicrobial agents. Development of this class of compounds has been shown to provide benefits especially from a biocidal point of, vie w. A novel s-triazine-based N-heterocycle, dichloro-m-aminophenyl-hydantoinyl-s-triazine (DAPHT), which could be rendered antimicrobial through exposure to diluted chlorine bleach, was synthesized and characterized by H-1 NMR, C-13 NMR, and FT-IR. A finishing method was used to apply the N-halamine precursor onto cotton fabric, and the optimum conditions for finishing were investigated. The DAPHT-treated cotton fabric had durable antimicrobial properties up to 50 standard washing cycles and was rechargeable under normal laundry/bleaching conditions. The antimicrobial efficacy against Gram-positive and Gram-negative bacteria was demonstrated.