Atom-transfer radical addition (ATRA) and cyclization (ATRC) reactions catalyzed by a mixture of [RuCl2Cp*(PPh3)] and magnesium

Thommes K., Icli B., Scopelliti R., Severin K.

CHEMISTRY-A EUROPEAN JOURNAL, cilt.13, sa.24, ss.6899-6907, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13 Sayı: 24
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1002/chem.200700442
  • Dergi Adı: CHEMISTRY-A EUROPEAN JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.6899-6907
  • Anahtar Kelimeler: catalysis, cyclization, magnesium, radical reactions, ruthenium, SUPPORTED ARYLNICKEL(II) CATALYSTS, MEDIUM-SIZED LACTONES, ARENESULFONYL CHLORIDES, HOMOGENEOUS CATALYSIS, SIMULTANEOUS REVERSE, SULFONYL CHLORIDES, NORMAL INITIATION, RUTHENIUM, COMPLEXES, OLEFINS
  • Orta Doğu Teknik Üniversitesi Adresli: Hayır

Özet

A new catalytic procedure for atom-transfer radical addition (ATRA) and cyclization (ATRC) reactions is described. The combination of the ruthenium(III) complex [RuCl2-Cp*(PPh3)] (Cp*: pentamethylcyclopentadienyl) with magnesium allows these reactions to be performed under mild conditions with high efficiency. In most cases, the catalyst concentrations required are significantly lower than those used in previously reported procedures. It is suggested that magnesium acts as a reducing agent that generates and regenerates the catalytically active ruthenium(II) species. ne precatalyst [RuCl2Cp*(PPh3)] has been analyzed by X-ray crystallography.