A direct injection method for blood cells into microchannels from pure blood droplets with switchable in-situ distillation of erythrocytes


Ciftlik A. T. , KÜLAH H.

Conference on PhD Research in Microelectronics and Electronics, İstanbul, Türkiye, 22 - 25 Haziran 2008, ss.29-32 identifier identifier

  • Doi Numarası: 10.1109/rme.2008.4595717
  • Basıldığı Şehir: İstanbul
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.29-32

Özet

This paper represents a direct injection method for leukocytes into microfluidic channels using negative dielectrophoresis. The blood sample is a heparinated pure blood droplet and injection is realized on-chip without any external microfluidic connections to the microchip. During injection erythrocytes are immobilized in-situ at injection reservoir electrodes. The method is easily applicable to most BioMEMS applications requiring direct injection of cells from pure blood and to eliminate pressure driven control.