pH-Responsive Nano Carriers for Doxorubicin Delivery


Bagherifam S., Skjeldal F. M. , Griffiths G., Maelandsmo G. M. , Engebraten O., Nystrom B., ...Daha Fazla

PHARMACEUTICAL RESEARCH, cilt.32, ss.1249-1263, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 32 Konu: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1007/s11095-014-1530-0
  • Dergi Adı: PHARMACEUTICAL RESEARCH
  • Sayfa Sayıları: ss.1249-1263

Özet

Purpose The aim of this study was to design stimuli-responsive nanocarriers for anti-cancer drug delivery. For this purpose, doxorubicin (DOX)-loaded, polysebacic anhydride (PSA) based nanocapsules (NC) were combined with pH-sensitive poly (L-histidine) (PLH).