pH-Responsive Nano Carriers for Doxorubicin Delivery


Bagherifam S., Skjeldal F. M. , Griffiths G., Maelandsmo G. M. , Engebraten O., Nystrom B., ...More

PHARMACEUTICAL RESEARCH, vol.32, no.4, pp.1249-1263, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 4
  • Publication Date: 2015
  • Doi Number: 10.1007/s11095-014-1530-0
  • Title of Journal : PHARMACEUTICAL RESEARCH
  • Page Numbers: pp.1249-1263

Abstract

Purpose The aim of this study was to design stimuli-responsive nanocarriers for anti-cancer drug delivery. For this purpose, doxorubicin (DOX)-loaded, polysebacic anhydride (PSA) based nanocapsules (NC) were combined with pH-sensitive poly (L-histidine) (PLH).