© 2021 World Scientific Publishing Company.Quantum dynamical properties of a general time-dependent coupled oscillator are investigated based on the theory of two-dimensional (2D) dynamical invariants. The quantum dynamical invariant of the system satisfies the Liouville-von Neumann equation and it coincides with its classical counterpart. The mathematical formula of this invariant involves a cross term which couples the two oscillators mutually. However, we show that, by introducing two pairs of annihilation and creation operators, it is possible to uncouple the original invariant operator so that it becomes the one that describes two independent subsystems. The eigenvalue problem of this decoupled quantum invariant can be solved by using a unitary transformation approach. Through this procedure, we eventually obtain the eigenfunctions of the invariant operator and the wave functions of the system in the Fock state. The wave functions that we have developed are necessary in studying the basic quantum characteristics of the system. In order to show the validity of our theory, we apply our consequences to the derivation of the fluctuations of canonical variables and the uncertainty products for a particular 2D oscillatory system whose masses are exponentially increasing.