Conversion of homochiral amines, beta-amino alcohols and alpha-amino acids to their chiral 2-substituted pyrrole derivatives

Demir, AYHAN; Akhmedov, IM; Sesenoglu, O; Alpturk, O; Apaydin, S; Gercek, Z; Ibrahimzade, N

doi:10.1039/b008317h

Conversion of homochiral amines, beta-amino alcohols and alpha-amino acids to their chiral 2-substituted pyrrole derivatives

Atıf İçin Kopyala

Demir A., Akhmedov I., Sesenoglu O., Alpturk O., Apaydin S., Gercek Z., ...Daha Fazla

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, sa.10, ss.1162-1167, 2001 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Basım Tarihi: 2001
Doi Numarası: 10.1039/b008317h
Dergi Adı: JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1162-1167
Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

The conversion of the amino group of chiral amines, amino alcohols, amino acids and their esters into chiral 2-substituted pyrrole derivatives with various halogeno enones is described. The conversion works in good yield and without racemization. The synthesis of 2-phenylpyrrole derivatives was possible with amino alcohols but not with amino acids or their esters.