COMPARATIVE-STUDIES OF SHEEP LUNG AND LIVER NITROFURANTOIN REDUCTASE

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ISCAN M.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY, vol.106, no.2, pp.579-584, 1993 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 106 Issue: 2
• Publication Date: 1993
• Doi Number: 10.1016/0742-8413(93)90182-k
• Journal Name: COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Animal Behavior Abstracts, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
• Page Numbers: pp.579-584
• Middle East Technical University Affiliated: Yes

Abstract

1. Nitrofurantoin reductase which catalyzes the bioactivation of nitrofurantoin was purified to electrophoretic homogenity from sheep liver and lung microsomes, with a yield of 15% and 35%, respectively. The specific activity of both reductases was found to be similar (140 nmol/min/mg protein).