COMPARATIVE-STUDIES OF SHEEP LUNG AND LIVER NITROFURANTOIN REDUCTASE


ISCAN M.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY, cilt.106, ss.579-584, 1993 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 106 Konu: 2
  • Basım Tarihi: 1993
  • Doi Numarası: 10.1016/0742-8413(93)90182-k
  • Dergi Adı: COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY
  • Sayfa Sayıları: ss.579-584

Özet

1. Nitrofurantoin reductase which catalyzes the bioactivation of nitrofurantoin was purified to electrophoretic homogenity from sheep liver and lung microsomes, with a yield of 15% and 35%, respectively. The specific activity of both reductases was found to be similar (140 nmol/min/mg protein).