Evaluation of [In-111]-Labeled Zinc-Dipicolylamine Tracers for SPECT Imaging of Bacterial Infection

Rice D. R., Plaunt A. J., Turkyilmaz S., Smith M., Wang Y., Rusckowski M., ...More

MOLECULAR IMAGING AND BIOLOGY, vol.17, no.2, pp.204-213, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 2
  • Publication Date: 2015
  • Doi Number: 10.1007/s11307-014-0758-8
  • Journal Name: MOLECULAR IMAGING AND BIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.204-213
  • Keywords: Zinc-dipicolylamine, Infection imaging, SPECT/CT, 111-indium, Molecular tracer, IN-VIVO, COORDINATION-COMPLEXES, IRON-OXIDE, PROBES, RECOGNITION, PARTICLES, ANTIBODY, AGENTS, VITRO, DTPA
  • Middle East Technical University Affiliated: No

Abstract

This study prepared three structurally related zinc-dipicolylamine (ZnDPA) tracers with [In-111] labels and conducted biodistribution and single-photon emission computed tomography/computed tomography (SPECT/CT) imaging studies of a mouse leg infection model.