Whole genome sequencing of Turkish genomes reveals functional private alleles and impact of genetic interactions with Europe, Asia and Africa

Alkan, Can; Kavak, Pinar; Somel, MEHMET; Gokcumen, Omer; Ugurlu, Serkan; Saygi, Ceren; Dal, Elif; Bugra, Kuyas; GÜNGÖR, TUNGA; Sahinalp, S.; ÖZÖREN, NESRİN; BEKPEN, CEMALETTİN

doi:10.1186/1471-2164-15-963

Whole genome sequencing of Turkish genomes reveals functional private alleles and impact of genetic interactions with Europe, Asia and Africa

Alkan C., Kavak P., Somel M., Gokcumen O., Ugurlu S., Saygi C., ...Daha Fazla

BMC GENOMICS, cilt.15, 2014 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 15
Basım Tarihi: 2014
Doi Numarası: 10.1186/1471-2164-15-963
Dergi Adı: BMC GENOMICS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

Background: Turkey is a crossroads of major population movements throughout history and has been a hotspot of cultural interactions. Several studies have investigated the complex population history of Turkey through a limited set of genetic markers. However, to date, there have been no studies to assess the genetic variation at the whole genome level using whole genome sequencing. Here, we present whole genome sequences of 16 Turkish individuals resequenced at high coverage (32 x -48x).