Biomimetic preparation of HA precursors at 37 degrees C in urea- and enzyme urease-containing synthetic body fluids

Bayraktar D., Tas A.

Symposium on Mineralization in Natural and Synthetic Biomaterials, Massachusetts, Amerika Birleşik Devletleri, 29 Kasım - 01 Aralık 1999, cilt.599, ss.159-164 identifier

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Cilt numarası: 599
  • Basıldığı Şehir: Massachusetts
  • Basıldığı Ülke: Amerika Birleşik Devletleri
  • Sayfa Sayıları: ss.159-164
  • Orta Doğu Teknik Üniversitesi Adresli: Hayır

Özet

An important inorganic phase of synthetic bone applications, calcium hydroxyapatite (HA, Ca-10(PO4)(6)(OH)(2)), was prepared as a single-phase and sub-micron bioceramic powder. Carbonated HA precursors were synthesized from calcium nitrate tetrahydrate and diammonium hydrogen phosphate salts dissolved in "synthetic body fluid" (SBF) solutions, containing urea (H2NCONH2) and enzyme urease, under the biomimetic conditions of 37 degrees C and pH 7.4, by using a novel chemical precipitation technique.