Chitosan Polysaccharide Suppress Toll Like Receptor Dependent Immune Response


Tincer G., Bayyurt B., Arica Y. M., Gursel I.

TURKISH JOURNAL OF IMMUNOLOGY, vol.3, no.1, pp.15-20, 2015 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 3 Issue: 1
  • Publication Date: 2015
  • Doi Number: 10.5606/tji.2015.329
  • Journal Name: TURKISH JOURNAL OF IMMUNOLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Page Numbers: pp.15-20
  • Keywords: Biomaterial, chitosan, double-stranded ribonucleic acid, innate immunity, polysaccharide, Toll like receptor 3, DELIVERY, ACTIVATION, CHITIN, INFLAMMASOME, SYSTEMS
  • Middle East Technical University Affiliated: No

Abstract

Objectives: Chitosan is a widely used vaccine or anti-cancer delivery vehicle. In this study, we investigated the immunomodulatory effect of chitosan/pIC nanocomplexes on mouse immune cells.