Ability of Sodium Dodecyl Sulfate (SDS) Micelles to Increase the Antioxidant Activity of α-Tocopherol

Inchingolo R., Bayram İ., ULUATA S., Kiralan S. S., Rodriguez-Estrada M. T., McClements D. J., ...More

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, vol.69, no.20, pp.5702-5708, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 69 Issue: 20
  • Publication Date: 2021
  • Doi Number: 10.1021/acs.jafc.1c01199
  • Journal Name: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Analytical Abstracts, Applied Science & Technology Source, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Chimica, Compendex, EMBASE, Environment Index, Food Science & Technology Abstracts, MEDLINE, Pollution Abstracts, Veterinary Science Database, DIALNET
  • Page Numbers: pp.5702-5708
  • Middle East Technical University Affiliated: No

Abstract

As emulsifiers become saturated on the surface of an emulsion droplet, any additional emulsifier migrates to the aqueous phase. Continuous phase surfactants have been shown to increase alpha-tocopherol efficacy, but it is unclear if this is the result of chemical or physical effects. The addition of alpha-tocopherol to an oil-in-water emulsion after homogenization resulted in a 70% increase of alpha-tocopherol in the continuous phase when sodium dodecyl sulfate (SDS) was at levels that were greater than the SDS critical micelle concentration. Conversely, when alpha-tocopherol was dissolved in the lipid before emulsification, continuous phase SDS concentrations did not increase. When SDS concentration led to an increase in the aqueous phase alpha-tocopherol, the oxidative stability of oil-in-water emulsions increased. Data indicated that the increased antioxidant activity was the result of surfactant micelles being able to decrease the prooxidant activity of alpha-tocopherol. Considering these results, surfactant micelles could be an important tool to increase the effectiveness of alpha-tocopherol.