Water-soluble green perylenediimide (PDI) dyes as potential sensitizers for photodynamic therapy

Yukruk F., Dogan A., Canpinar H., Guc D., Akkaya E.

ORGANIC LETTERS, vol.7, no.14, pp.2885-2887, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 14
  • Publication Date: 2005
  • Doi Number: 10.1021/ol050841g
  • Journal Name: ORGANIC LETTERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2885-2887
  • Middle East Technical University Affiliated: No

Abstract

A series of water-soluble green perylenediimide (PDI) dyes have been synthesized. On red light excitation, these dyes were shown to be efficient generators of singlet oxygen, and in cell culture media, they were shown to display significant light-induced cytotoxic effects on the human erythroleukemia cell line (K-562). It appears that highly versatile PDI dyes are likely to find new applications in photodynamic therapy.