Expression Profiles of the Individual Genes Corresponding to the Genes Generated by Cytotoxicity Experiments with Bortezomib in Multiple Myeloma

Ghasemi, Mehdi; Alpsoy, Semih; TÜRK TÜRK, SEYHAN; Malkan, Umit; Atakan, Sukru; HAZNEDAROĞLU, İBRAHİM; Gunes, Gursel; Gunduz, Mehmet; Yilmaz, Burak; Etgul, Sezgin; Aydin, Seda; Aslan, Tuncay; SAYINALP, NİLGÜN; AKSU, SALİH; DEMİROĞLU, HALUK; ÖZCEBE, OSMAN; BÜYÜKAŞIK, YAHYA; GÖKER, HAKAN

doi:10.4274/tjh.2015.0145

Expression Profiles of the Individual Genes Corresponding to the Genes Generated by Cytotoxicity Experiments with Bortezomib in Multiple Myeloma

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Ghasemi M., Alpsoy S., TÜRK TÜRK S., Malkan U. Y., Atakan S., HAZNEDAROĞLU İ. C., ...More

TURKISH JOURNAL OF HEMATOLOGY, vol.33, no.4, pp.286-292, 2016 (SCI-Expanded)

Publication Type: Article / Article
Volume: 33 Issue: 4
Publication Date: 2016
Doi Number: 10.4274/tjh.2015.0145
Journal Name: TURKISH JOURNAL OF HEMATOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Page Numbers: pp.286-292
Middle East Technical University Affiliated: No

Abstract

Objective: Multiple myeloma (MM) is currently incurable due to refractory disease relapse even under novel anti-myeloma treatment. In silico studies are effective for key decision making during clinicopathological battles against the chronic course of MM. The aim of this present in silico study was to identify individual genes whose expression profiles match that of the one generated by cytotoxicity experiments for bortezomib.