In vitro cytotoxicity, corrosion and antibacterial efficiencies of Zn doped hydroxyapatite coated Ti based implant materials

Buyuksungur S., YILGÖR HURİ P., Schmidt J., Pana I., Dinu M., Vitelaru C., ...More

Ceramics International, vol.49, no.8, pp.12570-12584, 2023 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 8
  • Publication Date: 2023
  • Doi Number: 10.1016/j.ceramint.2022.12.119
  • Journal Name: Ceramics International
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Chemical Abstracts Core, Communication Abstracts, INSPEC, Metadex, Civil Engineering Abstracts
  • Page Numbers: pp.12570-12584
  • Keywords: Film, Interfaces, Corrosion, Apatite, Biomedical applications, SURFACE FREE-ENERGY, VIVO BIOCOMPATIBILITY, ZINC, DEPOSITION, SCAFFOLDS, COATINGS, FILMS, AG
  • Middle East Technical University Affiliated: Yes


© 2022 Elsevier Ltd and Techna Group S.r.l.Ti6Al4V alloy is successfully used as implant material in dental and orthopedic surgeries for years due to its much better compatibility, lower density, corrosion resistance, etc. compared to the other metals. Meantime, modification of the surface of these alloys is needed to enhance material-tissue interaction and osteointegration between the implant and the bone. In this study, Ti6Al4V alloy surfaces were modified by application of RF magnetron sputtering technique and coated with zinc (Zn) doped hydroxyapatite (HAp). The obtained coating was very stable with highly crystalline structure, demonstrated enhanced corrosion resistance, osteointegration and antimicrobial effectiveness against Escherichia coli (E. coli) bacteria.