ARID3B expression in primary breast cancers and breast cancer-derived cell lines


ERDOGAN A. S. O. , OZDEMIRLER N., ÖYKEN M. , ALPER M., Erson-Bensan A. E.

CELLULAR ONCOLOGY, cilt.37, ss.289-296, 2014 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 37 Konu: 4
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1007/s13402-014-0185-5
  • Dergi Adı: CELLULAR ONCOLOGY
  • Sayfa Sayısı: ss.289-296

Özet

ARID3B (AT-rich interaction domain 3) is a member of the family of ARID proteins, which constitutes evolutionarily conserved transcription factors implicated in normal development, differentiation, cell cycle regulation and chromatin remodeling. In addition, ARID3B has been linked to cellular immortalization, epithelial-mesenchymal transition (EMT) and tumorigenesis. Given the emerging role of ARID3B in tumor development, we examined its expression in primary patient-derived breast cancer samples and breast cancer-derived cell lines.