ARID3B expression in primary breast cancers and breast cancer-derived cell lines

ERDOGAN A. S. O., OZDEMIRLER N., ÖYKEN M., ALPER M., Erson-Bensan A. E.

CELLULAR ONCOLOGY, cilt.37, sa.4, ss.289-296, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 4
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1007/s13402-014-0185-5
  • Dergi Adı: CELLULAR ONCOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.289-296
  • Anahtar Kelimeler: ARID3B expression, Breast cancer, Estrogen receptor, ERBB2, DNA-BINDING PROTEINS, FAMILY, MIR-125A, GROWTH, MIRNAS
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

ARID3B (AT-rich interaction domain 3) is a member of the family of ARID proteins, which constitutes evolutionarily conserved transcription factors implicated in normal development, differentiation, cell cycle regulation and chromatin remodeling. In addition, ARID3B has been linked to cellular immortalization, epithelial-mesenchymal transition (EMT) and tumorigenesis. Given the emerging role of ARID3B in tumor development, we examined its expression in primary patient-derived breast cancer samples and breast cancer-derived cell lines.