Indenoquinoxalinone based conjugated polymer substrate for laccase biosensor

Cevher Ş. C., Bekmezci S. A., SaniyeSoylemez S., Udum Y. A., Toppare L. K., ÇIRPAN A.

MATERIALS CHEMISTRY AND PHYSICS, cilt.257, 2021 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 257
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1016/j.matchemphys.2020.123788
  • Dergi Adı: MATERIALS CHEMISTRY AND PHYSICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Chemical Abstracts Core, Communication Abstracts, INSPEC, Metadex, Civil Engineering Abstracts
  • Anahtar Kelimeler: Indenoquinoxalinone based conducting polymer, Electrochemistry, Laccase biosensor, Catechol detection, SIDE-CHAINS, ELECTRODE, IMMOBILIZATION, CHITOSAN, DESIGN
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

This paper describes the synthesis and characterization of a novel monomer (6,9-bis(4-hexylthiophen-2-yl)-1-1H-indeno [2,1-b]quinoxalin-11-one (M1)). M1 monomer was electrochemically polymerized on the electrode surface and used as a sensing platform for the immobilization of laccase. Moreover, electrochemical and optical properties of the corresponding polymer were performed in detail. To the best of our knowledge, electrochemical and biosensor performance of the polymer were investigated for the first time. The PM1/Laccase were used in the fabrication of a new biosensor for determination of catechol in water samples by ampemmetric methods. Under optimized conditions, the calibration curve showed a linear range of 0.005-0.175 mM, with a limit of detection of 9.86 mu M and high sensitivity of 153.6 mu A/mMcm(2). The biosensor exhibited good stability, selectivity and high sensitivity toward catechol.