Synthetic biology for therapeutics: Engineering cells for living drugs
- Publication Type: Book / Research Book
- Publication Date: 2024
- Doi Number: 10.1515/9783111329499
- Publisher: De Gruyter
- Keywords: Biological devices, Cellular targeting, Mammalian cells, Microbial cells, Programming cells
- Middle East Technical University Affiliated: No
Abstract
Synthetic biology is enabling scientists to use engineered genetic circuits in the cells as the basis for the development of new living therapeutics and as a powerful new weapon in the fight against diseases, especially cancer. Bacteria-mediated therapy is a promising alternative cancer treatment. The book covers the recent developments of cellular therapies from a synthetic biology perspective including engineered microbial therapies, CAR-T therapies etc. and is an indispensable guide to scientists in both biotechnology and medicine. • Synthetic biology applications in programming cells and developing living drugs. • Biological devices for cellular targeting. • Engineering mammalian and microbial cells for cancer therapies.