Ceria supported ruthenium nanoparticles (Ru-0/CeO2) are synthesized by impregnation of Ru3+ ions on CeO2 powders followed by sodium borohydride reduction of Ru3+/CeO2. Their characterization was achieved using analytical methods including TEM, XRD, BET, SEM, and XPS. All the results reveal the formation of ruthenium(0) nanoparticles in 1.8 +/- 0.3 nm size on CeO2 support. Ru-0/GeO2 nanoparticles show high activity in catalyzing the H-2 evolution from dimethylamine borane (DMAB). Ru-0/CeO2 nanoparticles with 0.55% wt Ru provide the highest turnover frequency (812 h(-1)) for releasing H-2 from DMAB at 60 degrees C and a total of 2500 turnovers before deactivation. High activity of Ru-0/CeO2 nanoparticles for catalytic dehydrogenation of DMAB is attributable to the reducible nature of CeO2 support. Ce3+ defects formation in ceria under reducing conditions of dehydrogenation causes accumulation of negative charge on the oxide support, which makes oxide surface attractive for the ruthenium(0) nanoparticles. This, in turn, causes an enhancement in the metal-support interaction and thus in catalytic activity. The XPS analysis of bare ceria and Ru-0/CeO2 demonstrates the increase in the concentration of Ce3+ defects after catalysis. Ru-0/CeO2 nanoparticles are also reusable catalyst for H-2 evolution from DMAB retaining 40% of initial activity after 4th run of reaction. The catalytic activity of Ru-0/CeO2 nanoparticles and activation energy of catalytic dehydrogenation are compared with those of the other ruthenium based catalysts known in literature. (C) 2019 Hydrogen Energy Publications LLC. Published by Elsevier Ltd. All rights reserved.