The synthesis of unusual isocoumarin derivatives: the chemistry of homophthalic acid

Ozcan S., Sahin E., Balci M.

TETRAHEDRON LETTERS, vol.48, no.12, pp.2151-2154, 2007 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 12
  • Publication Date: 2007
  • Doi Number: 10.1016/j.tetlet.2007.01.098
  • Journal Name: TETRAHEDRON LETTERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2151-2154
  • Keywords: homophthalic acid, isocoumarin, dibenzocromenone, sodium azide, acyl azide, HYDRANGEAE-DULCIS FOLIUM, ALPHA-PYRONES, ANTIFUNGAL, CYCLIZATION
  • Middle East Technical University Affiliated: No

Abstract

Homophthalic acid was reacted with thionyl chloride/DMF and ethyl chloroformate/NEt3 in the presence and absence of NaN3. In all cases completely different isocoumarin derivatives were obtained. These unusual isocournarin derivatives were characterized and their mechanism of formation is discussed. (c) 2007 Elsevier Ltd. All rights reserved.