In this paper, we present the results from a Suzaku observation of the Galactic supernova remnant G272.2-3.2. The spectra of G272.2-3.2 are well fitted by a single-temperature variable abundance non-equilibrium ionization (VNEI) model with an electron temperature kTe similar to 0.77 keV, an ionization time-scale t similar to 6.5 x 1010 cm-3 s and an absorbing column density NH similar to 1.1 x 1022 cm-2. We have detected enhanced abundances of Si, S, Ca, Fe and Ni in the centre region, indicating that the X-ray emission has an ejecta origin. We estimate that the electron density is ne similar to 0.48f-1/2 cm-3, the age is similar to 4300f1/2 yr and the X-ray total mass is Mx= 475f1/2 M circle dot by taking the distance to be d= 10 kpc. To understand the origin of the centrally peaked X-ray emission of the remnant, we have studied the radial variations of the electron temperature and surface brightness. The relative abundances in the centre region suggest that G272.2-3.2 is the result of a Type Ia supernova explosion.