Quantum chemical studies on certain mitomycins - AM1 treatment


Turker L.

JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM, cilt.542, ss.247-253, 2001 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 542
  • Basım Tarihi: 2001
  • Doi Numarası: 10.1016/s0166-1280(00)00854-x
  • Dergi Adı: JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM
  • Sayfa Sayıları: ss.247-253

Özet

Mitomycin-C, a widely used antitumor antibiotic, and its analogues mitomycin-A and porfiromycin are considered for AM1-RHF type semiempirical quantum chemical treatment. The structural and energetic aspects, as well as certain molecular orbital characteristics of these structures have been compared. (C) 2001 Elsevier Science B.V. All rights reserved.