Self-condensation reactions of acyl phosphonates: synthesis of tertiary O-protected alpha-hydroxyphosphonates

EYMUR S., Gollu M., Demir A. S.

TURKISH JOURNAL OF CHEMISTRY, vol.38, no.1, pp.164-171, 2014 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 1
  • Publication Date: 2014
  • Doi Number: 10.3906/kim-1306-7
  • Journal Name: TURKISH JOURNAL OF CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded, Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.164-171
  • Keywords: Acyl phosphonates, tertiary alpha-hydroxy phosphonates, phosphonate-phosphate rearrangement, ENANTIOSELECTIVE SYNTHESIS, ASYMMETRIC-SYNTHESIS, HYDROXY PHOSPHONATES, ANION EQUIVALENTS, DERIVATIVES, INHIBITORS, STATE, ACYLPHOSPHONATES, OXIDATION

Abstract

The self-condensation reaction of benzoyl dialkyl phosphonates was developed using cyanide ion as catalyst, affording versatile tertiary O-protected alpha-hydroxy phosphonates in moderate yield.