Two Types of Block Copolymer Micelles with Ion-Containing Cores

Erel I., Zhu Z., Sukhishvili S., PATYUKOVA E., Potemkin I., KRAMARENKO E.

MACROMOLECULAR RAPID COMMUNICATIONS, cilt.31, sa.5, ss.490-495, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 5
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1002/marc.200900659
  • Dergi Adı: MACROMOLECULAR RAPID COMMUNICATIONS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.490-495
  • Anahtar Kelimeler: amphiphiles, diblock copolymers, micelles, polyelectrolytes, self-assembly, AQUEOUS-SOLUTION PROPERTIES, DIBLOCK COPOLYMERS, HOFMEISTER SERIES, SOLVENT, MACROMOLECULES, METHACRYLATES, COLLAPSE, BEHAVIOR, BRUSHES, ATRP
  • Orta Doğu Teknik Üniversitesi Adresli: Hayır

Özet

We report a combined experimental and theoretical study of micellization of block copolymer with hydrophilic nonionic corona-forming blocks and weak polyelectrolyte (wPE) core-forming blocks with pH-triggered solubility in aqueous solutions. We demonstrate that in addition to micelles with neutral cores, there exist two other types of micelles with PE- or ionomer-like cores, in which monovalent counterions are released or condensed on core wPE block, respectively. The transition between the two types of micelles occurred upon changes in ionization of the PE core block and resulted in nonmonotonous changes of aggregation number as a function of pH. Such micelles with stimulus responsive cores represent promising nanocarriers for controlled delivery applications.