Estimation of human daily boron exposure in a boron-rich area

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Korkmaz M., Sayli U., Sayli B. S. , Bakirdere S., Titretir S., Ataman O. Y. , ...More

BRITISH JOURNAL OF NUTRITION, vol.98, no.3, pp.571-575, 2007 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 98 Issue: 3
  • Publication Date: 2007
  • Doi Number: 10.1017/s000711450770911x
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.571-575
  • Keywords: boron, daily exposure, risk assessment, DIETARY BORON, BORIC-ACID, DEVELOPMENTAL TOXICITY, CELLS, BORAX, RISK, BONE, RATS


Although, the safe limits of human daily boron (B) exposure are not absolutely clear, there is a growing interest in B and its effects on human health. The aim of the present study was to estimate daily B exposure in 66 males in Turkey living in a B-rich area using water containing at least 2 mg/1 boron, with an average age of 38-55 (SE 1.66) years and an average number of years of residence in the B-rich area of 35-89 (SE 1.73). Another group of males (n 57), living in the city centres of Balikesir and Ankara, were taken as controls; the average age and number of years of residence for this group were 29-44 (SE 1-43) and 10-26 (SE 1.83) years, respectively. As it is assumed that the B level in urine reflects daily B exposure, the amount of urinary B of both the study and control groups was analysed by using an inductively coupled plasma optical emission spectrometry (ICP-OES) technique. The average daily B exposure value was calculated as 6.77 (SE 0.47) mg in the study group and 1.26 (SE 0-1) mg in the controls. The results of this study are expected to contribute to creating a reference value for a safe daily B exposure.