Atlas of Genetics and Cytogenetics in Oncology and Haematology, vol.23, no.6, pp.137-142, 2019 (Scopus)
Heterogeneous nuclear ribonucleoprotein (HNRNPA1) gene maps to
chromosome 12, plus strand and has 13 exons and 12 introns. There are
three reported transcripts due to the alternative splicing.
HNRNPA1
is one of the most abundant and ubiquitously expressed nuclear
proteins. HNRNPA1 is a member of RNA-binding protein family comprising
of 20 members in humans (Dreyfuss, 1993; Pinol-Roma, Choi, Matunis,
& Dreyfuss, 1988). HNRNPA1 has diverse roles in RNA splicing,
telomere length maintenance, miRNA maturation and mRNA transport from
nucleus to cytoplasm.