Type I IFN-related NETosis in ataxia telangiectasia and Artemis deficiency

Gul, Ersin; Sayar, Esra; Gungor, Bilgi; Eroglu, Fehime; Surucu, Naz; Keleş, Sevgi; Güner, Şükrü; Findik, Siddika; Alpdundar, Esin; Ayanoğlu, İHSAN; Kayaoğlu, BAŞAK; Geckin, Busra; Sanli, Hatice; Kahraman, Tamer; Yakicier, Cengiz; Müftüoğlu, Meltem; Oğuz, Berna; Çağdaş Ayvaz, Deniz; Gürsel, İhsan; Özen, Seza; Reisli, İsmail; Gürsel, MAYDA

doi:10.1016/j.jaci.2017.10.030

Type I IFN-related NETosis in ataxia telangiectasia and Artemis deficiency

Gul E., Sayar E. H., Gungor B., Eroglu F. K., Surucu N., Keleş S., ...Daha Fazla

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, cilt.142, ss.246-257, 2018 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 142
Basım Tarihi: 2018
Doi Numarası: 10.1016/j.jaci.2017.10.030
Dergi Adı: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.246-257
Anahtar Kelimeler: Primary immunodeficiencies, autoinflammation, ataxia telangiectasia, Artemis deficiency, type I IFN, interferonopathy, neutrophil extracellular traps, NETosis, NEUTROPHIL EXTRACELLULAR TRAPS, SYSTEMIC-LUPUS-ERYTHEMATOSUS, ACUTE MYOCARDIAL-INFARCTION, COMBINED IMMUNODEFICIENCY, CUTANEOUS GRANULOMAS, MITOCHONDRIAL-DNA, DCLRE1C MUTATIONS, DISEASE, DAMAGE, INTERFERONOPATHIES
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

Background: Pathological inflammatory syndromes of unknown etiology are commonly observed in ataxia telangiectasia (AT) and Artemis deficiency. Similar inflammatory manifestations also exist in patients with STING-associated vasculopathy in infancy (SAVI).