Characterization of Leiurus abdullahbayrami (Scorpiones: Buthidae) venom: peptide profile, cytotoxicity and antimicrobial activity

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ERDES E., Dogan T., Cosar I., Danisman T., Kunt K. B., ŞEKER T., ...More

JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES, vol.20, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20
  • Publication Date: 2014
  • Doi Number: 10.1186/1678-9199-20-48
  • Journal Name: JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: Scorpion venom, Toxin, Peptide, Leiurus abdullahbayrami, Microfluidic capillary, Electrophoresis, Peptidomics, Venomics, Cytotoxicity, Antimicrobial activity, Turkey, ANDROCTONUS-CRASSICAUDA, SPIDER-VENOM, PURIFICATION, COMPONENTS, INHIBITOR, CHANNELS, DATABASE, TOXINS
  • Middle East Technical University Affiliated: Yes

Abstract

Background: Scorpion venoms are rich bioactive peptide libraries that offer promising molecules that may lead to the discovery and development of new drugs. Leiurus abdullahbayrami produces one of the most potent venoms among Turkish scorpions that provokes severe symptoms in envenomated victims.