The effects of local and sustained release of fibroblast growth factor on wound heating in esophageal anastomoses

Fedakar-Senyucel M., Bingo-Kologlu M., Vargun R., Akbay C., Sarac F. N., Renda N., ...Daha Fazla

JOURNAL OF PEDIATRIC SURGERY, cilt.43, sa.2, ss.290-295, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43 Sayı: 2
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.jpedsurg.2007.10.016
  • Dergi Adı: JOURNAL OF PEDIATRIC SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.290-295
  • Anahtar Kelimeler: esophagus, anastomosis, FGF, wound healing, ATRESIA, HYDROGEL, GELATIN, TISSUE
  • Orta Doğu Teknik Üniversitesi Adresli: Evet

Özet

Background/ Purpose: Postsurgical complications, such as anastomotic leaks in patients with esophageal atresia, have remained unchanged during the last 3 decades. Growth factors enhance healing in several wound-healing models. Therefore, an experimental study was used to evaluate the effects of local and sustained release of basic fibroblast growth factor (FGF) on wound healing in esophageal anastomoses.