Akademik Veri Yönetim Sistemi
Plasmonic Nanosensors for Biological and Chemical Threats, CRC Press, ss.55-90, 2024
Synthetic biology, which encompasses the design and construction of new biological components and the refinement of existing systems, has opened a new area of development for the biosensing of chemical and biological threats. In this chapter, we list and summarize the developments and challenges overcome in biosensing applications through the use of synthetic biology-based tools and research for detecting chemical and biological threats in recent years. First, we will focus on cell-based biosensors, their applications in biomedicine, environmental monitoring, and industrial processes, and the present challenges. Next, we will explore cell-free methods and their integration with traditional methods for detecting chemical and biological threats. Later, we will move from platforms to tools and components and elaborate on nucleic acid-based biosensors used to detect these threats, including aptamer-based and CRISPR-Cas-based (clustered regularly interspaced short palindromic repeats associated Cas enzymes) biosensors. Lastly, we will mention general insights on synthetic biology studies for chemical and biological threats and how the field, with forthcoming technologies such as artificial intelligence, can revolutionize biosensing and biosensor design.