A direct injection method for blood cells into microchannels from pure blood droplets with switchable in-situ distillation of erythrocytes

Ciftlik A. T., KÜLAH H.

Conference on PhD Research in Microelectronics and Electronics, İstanbul, Turkey, 22 - 25 June 2008, pp.29-32 identifier identifier

  • Publication Type: Conference Paper / Full Text
  • Doi Number: 10.1109/rme.2008.4595717
  • City: İstanbul
  • Country: Turkey
  • Page Numbers: pp.29-32
  • Middle East Technical University Affiliated: Yes

Abstract

This paper represents a direct injection method for leukocytes into microfluidic channels using negative dielectrophoresis. The blood sample is a heparinated pure blood droplet and injection is realized on-chip without any external microfluidic connections to the microchip. During injection erythrocytes are immobilized in-situ at injection reservoir electrodes. The method is easily applicable to most BioMEMS applications requiring direct injection of cells from pure blood and to eliminate pressure driven control.