Akademik Veri Yönetim Sistemi
Tezin Türü: Yüksek Lisans
Tezin Yürütüldüğü Kurum: Orta Doğu Teknik Üniversitesi, Fen Edebiyat Fakültesi, Kimya Bölümü, Türkiye
Tezin Onay Tarihi: 2006
Tezin Dili: İngilizce
Öğrenci: Fadile Kapaklı
Danışman: CİHANGİR TANYELİ
Özet:Pyrroles are very valuable class of substances which have wide usage area in organic synthesis. In this study, chiral 3,4-dialkoxy-N-substituted pyrrole derivatives were synthesized. These compounds are widely used as building blocks for the synthesis of natural compounds that have focused on heterocyclic rings in their structures. In addition, chiral pyrrole derivatives can be used as monomers for the synthesis of chiral conducting polymers which have received great interest due to their potential applications as electrodes for electrochemical asymmetric synthesis, stereoselecive analyses and in many areas, such as electronics, electrochromic devices, polymeric batteries, antielectronic coatings and functional membranes. 3,4-dialkoxy-N-substituted chiral pyrrole derivatives were synthesized starting from 2,5-dimethoxy-2,5-dihydrofuran which is a commercially available, inexpensive material. After oxidation, the resultant diol were protected with alkoxy goups and then correponding 3,4-dialkoxy-N-substituted chiral pyrrole derivatives were afforded via pyrrolization reaction by using several chiral amines or aminoalcohols.